منابع مشابه
Investigation of Intestinal Absorption of Pyridinones in Rat
Recently, it has been shown that a number of hydroxypyridinones such as 1,2-dimethyl-3-hydroxypyridin-4-one (L1) are useful for the treatment of iron overload in place of desferrioxamine in thalassaemic patients. In this study, the intestinal absorption (I.A.) of L1 and one of its analogues namely 2-methy-3-hydroxypyridin-4-one (L2), which possesses a higher partition coefficient (Kpart) than L...
متن کاملInvestigation of Intestinal Absorption of Pyridinones in Rat
Recently, it has been shown that a number of hydroxypyridinones such as 1,2-dimethyl-3-hydroxypyridin-4-one (L1) are useful for the treatment of iron overload in place of desferrioxamine in thalassaemic patients. In this study, the intestinal absorption (I.A.) of L1 and one of its analogues namely 2-methy-3-hydroxypyridin-4-one (L2), which possesses a higher partition coefficient (Kpart) than L...
متن کاملINTESTINAL ZINC ABSORPTION IN DESFERROXAMINE-TREATED RATS
Desferroxamine (Desferal) is used tochelate iron in thalassemia, a disease of very high prevalence in various parts of lran. We have investigated intestinal zinc absorption in Desferal-treated rats which, in pilot experiments, showed low serum levels of both iron and zinc. Intraperitoneal administration of ten 0.5 g doses of Desferal (one injection every other day) to male rats produced sev...
متن کاملIntestinal Absorption of Fats.
Great progress in understanding the mechanisms of fat absorption by the mammalian intestine has been made in the past decade and a half. In contrast to the contentions of rival theorists of the century before this, it has been possible for many laboratories throughout the world to confirm observations made by use of the new tools available, and to come to agreement on current interpretations of...
متن کاملIntestinal Folate Absorption
and 2%, respectively, was converted to 5-AMeFH4. In contrast, less than 4% of the folate transferred across ileal mucosa was 5-MeFH4 when the initial mucosa concentration was 20 nM. Specific activity of dihydrofolate (DHF) reductase, the enzyme responsible for converting PGA to tetrahydrofolic acid, was measured in villus homogenates and was significantly greater in the jejunum than in the ileu...
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ژورنال
عنوان ژورنال: Reproduction Nutrition Développement
سال: 1980
ISSN: 0181-1916
DOI: 10.1051/rnd:19800720